| Bioactivity | OS-3-106 is a potent, BBB-penetrated and selective dopamine D3 receptor (D3R) agonist. OS-3-106 binds with high affinity (Ki = 0.2 nM) at the D3R. OS-3-106 reduces cocaine self-administration and sucrose reinforcement rates. OS-3-106 can be used for psychostimulant addiction research[1]. |
| Invitro | OS-3-106 exhibits 115-fold binding selectivity for the D3R compared with the D2R[1]. |
| Name | OS-3-106 |
| CAS | 1580000-17-4 |
| Formula | C25H30N4O2S |
| Molar Mass | 450.60 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cheung TH, et al. Reduction of cocaine self-administration and D3 receptor-mediated behavior by two novel dopamine D3 receptor-selective partial agonists, OS-3-106 and WW-III-55. J Pharmacol Exp Ther. 2013 Nov;347(2):410-23. |
OS-3-106
CAS: 1580000-17-4 F: C25H30N4O2S W: 450.60
OS-3-106 is a potent, BBB-penetrated and selective dopamine D3 receptor (D3R) agonist. OS-3-106 binds with high affinity
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.