| Bioactivity | OMS14 is exhibits inhibitory activity for phosphoinositide 3-kinase γ (PI3Kγ) and PIK3CD/PIK3R1, which inhibits 19% PI3Kγ and 65% PIK3CD/PIK3R1 activity at 100 μM. OMS14 exhibits anticancer efficacy in various cancer cells[1]. |
| Invitro | OMS14 (0-100 μM) 抑制细胞 A549 和 MCF-7 的增殖，IC50 分别为 22.13 和 26.09 μM[1]。OMS14 (100 μg/mL) 抑制 Staphylococcus aureus 菌落的形成，抑制直径为 15 mm[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> OMS14 相关抗体: Cell Viability Assay[1] Cell Line: |
| Formula | C21H22N6O4S |
| Molar Mass | 454.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Salih O M, et al., Novel 2-Aminobenzothiazole Derivatives: Docking, Synthesis, and Biological Evaluation as Anticancer Agents[J]. ACS Omega, 2024. |