| Bioactivity | Nrf2 activator-6, a tetrahydroisoquinoline compound, is a Nrf2 activator. Nrf2 activator-6 has an IC50 of 5 nM for inhibiting the Kelch domain-Nrf2 interaction (WO2021214470A1; Example 4)[1]. |
| Invitro | Nrf2 activator-6 (Example 4) 增加 NRF2 介导的基因 NADPH：醌受体氧化还原酶 1 (NQO1) 的 mRNA 水平，EC50 为 0.3 nM[1]。 |
| Name | Nrf2 activator-6 |
| CAS | 2728780-74-1 |
| Formula | C31H37ClFN5O5 |
| Molar Mass | 614.11 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cathy Louise LUCAS, et al. Tetrahydroisoquinoline compounds as nrf2 activators. WO2021214470A1. |
Nrf2 activator-6
CAS: 2728780-74-1 F: C31H37ClFN5O5 W: 614.11
Nrf2 activator-6, a tetrahydroisoquinoline compound, is a Nrf2 activator. Nrf2 activator-6 has an IC50 of 5 nM for inhib
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