PeptideDB

Nisin

CAS: 1414-45-5 F: C143H230N42O37S7 W: 3354.07

Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus speci
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Bioactivity Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus species.
Invitro Nisin is classified as a Type A (I) lantibiotic that is synthesized from mRNA and the translated peptide contains several unusual amino acids due to post-translational modifications. Nisin is an antimicrobial peptide produced by certain Gram-positive bacteria that include Lactococcus and Streptococcus species[1].
Name Nisin
CAS 1414-45-5
Sequence Ile-{Abu}-{d-Cys}-Ile-Ala-Leu-Cys-{d-Abu}-Pro-Gly-Cys-Lys-{d-Abu}-Gly-Ala-Leu-Met-Gly-Cys-Asn-Met-Lys-{d-Abu}-Ala-{d-Abu}-Cys-His-Cys-Ser-Ile-His-Val-Ala-Lys (Disulfide bridge: Cys3-Cys7, Abu8-Cys11, Abu13-Cys19, Abu23-Cys26, Abu25-Cys28)
Shortening I-{Abu}-{d-Cys}-IALC-{d-Abu}-PGCK-{d-Abu}-GALMGCNML-{d-Abu}-A-{d-Abu}-CHCSIHVAK (Disulfide bridge: Cys3-Cys7, Abu8-Cys11, Abu13-Cys19, Abu23-Cys26, Abu25-Cys28)
Formula C143H230N42O37S7
Molar Mass 3354.07
Transport Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)