| Bioactivity | Ninerafaxstat (IMB-1018972) trihydrochloride is a cardiac mitotrope agent. Ninerafaxstat trihydrochloride increases myocardial metabolic efficiency by shifting substrate utilization towards glucose through reducing fatty acid oxidation (inhibiting 3-ketoacyl CoA thiolase)[1]. |
| Name | Ninerafaxstat trihydrochloride |
| CAS | 2311824-72-1 |
| Formula | C22H32Cl3N3O5 |
| Molar Mass | 524.87 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Larry Tremaine, et al. Abstract 10372: A Clinical Drug-Drug Interaction Study of Imb-1018972, a Novel Investigational Cardiac Mitotrope in Phase 2 Development for the Treatment of Myocardial Ischemia and Hypertrophic Cardiomyopathy. METABOLISM AND PHYSIOLOGY. 8 Nov 2021. |
Ninerafaxstat trihydrochloride
CAS: 2311824-72-1 F: C22H32Cl3N3O5 W: 524.87
Ninerafaxstat (IMB-1018972) trihydrochloride is a cardiac mitotrope agent. Ninerafaxstat trihydrochloride increases myoc
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