| Bioactivity | Nictide is a peptide substrate of LRRK2 (leucine-rich repeat protein kinase-2). Nictide can be phosphorylated by the activated LRRK2[G2019S] with a Km of 10 μM[1]. |
| CAS | 1159973-22-4 |
| Sequence | Arg-Leu-Gly-Trp-Trp-Arg-Phe-Tyr-Thr-Leu-Arg-Arg-Ala-Arg-Gln-Gly-Asn-Thr-Lys-Gln-Arg |
| Shortening | RLGWWRFYTLRRARQGNTKQR |
| Formula | C123H193N45O28 |
| Molar Mass | 2750.13 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. R. Jeremy Nichols, et al. Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson’s disease. Biochem J. 2009 Oct 23; 424(1): 47–60. |
Nictide
CAS: 1159973-22-4 F: C123H193N45O28 W: 2750.13
Nictide is a peptide substrate ofLRRK2 (leucine-rich repeat protein kinase-2). Nictide can be phosphorylated by the acti
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