| Bioactivity | LAS195319 is a potent inhibitor against PI3Kδ with an IC50 value of 0.5 nM. LAS195319 is also a highly selective inhibitor against an extensive panel of proteins, lipid kinases and GPCRs. LAS195319 causes an inhibition of neutrophil and eosinophil infiltration. LAS195319 is promising for research of respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD)[1]. |
| CAS | 1605328-04-8 |
| Formula | C29H26N10O3S |
| Molar Mass | 594.65 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Erra M, et al. Discovery of a Novel Inhaled PI3Kδ Inhibitor for the Treatment of Respiratory Diseases. J Med Chem. 2018 Nov 8;61(21):9551-9567. |
LAS195319
CAS: 1605328-04-8 F: C29H26N10O3S W: 594.65
LAS195319 is a potent inhibitor against PI3Kδ with an IC50 value of 0.5 nM. LAS195319 is also a highly selective inhibi
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