Neuropeptide Y (3-36) (porcine)

CAS: 143863-88-1 F: C176H271N53O54 W: 3993.36

Neuropeptide Y (3-36) (porcine) is an agonist of neuropeptide Y (NPY) receptor subtype Y2, and stimulates feeding in rat

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Bioactivity	Neuropeptide Y (3-36) (porcine) is an agonist of neuropeptide Y (NPY) receptor subtype Y2, and stimulates feeding in rats. Neuropeptide Y (3-36) (porcine) is a highly Y2 selective ligand compared with nselective Y1/Y2 receptor ligand, Neuropeptide Y 1-36[1][2][3].
Invitro	Neuropeptide Y (3-36) (porcine) accounts for 35% of NPY-like immunoreactivity in porcine brain[2]. Neuropeptide Y (3-36) (porcine) shows high affinity for Y2-like receptors on CHP234 cells, and light affinity Y1-like receptors on SK-N-MC cells[2].
In Vivo	Neuropeptide Y (3-36) (porcine) (0.24-24 nM; i.c.v.; single dose) induces feeding in the rat in a dose-dependent manner[1]. Neuropeptide Y (3-36) (porcine) (4 μg, 8 μg; i.c.v.; single dose) significantly increased food intake at 2 and 3 h, results dose-dependently orexigenic effect in rainbow trout (Oncorhynchus mykiss)[2]. Animal Model:
Name	Neuropeptide Y (3-36) (porcine)
CAS	143863-88-1
Shortening	SKPDNPGEDAPAEDLARYYSALRHYINLITRQRY-NH2
Formula	C176H271N53O54
Molar Mass	3993.36
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. O'Shea D, et al. Neuropeptide Y induced feeding in the rat is mediated by a novel receptor. Endocrinology. 1997 Jan;138(1):196-202. [2]. Grandt D, et al. Neuropeptide Y 3-36 is an endogenous ligand selective for Y2 receptors. Regul Pept. 1996 Nov 14;67(1):33-7. [3]. M Aldegunde, et al. Effects of neuropeptide Y on food intake and brain biogenic amines in the rainbow trout (Oncorhynchus mykiss), Peptides. 2006; 27(4):719-727.

(1S,2R)-Tranylcypromine hydrochloride