| Bioactivity | (1S,2R)-Tranylcypromine ((1S,2R)-SKF 385) hydrochloride is a potent antidepressant agent. (1S,2R)-Tranylcypromine hydrochloride can inhibits MAO and LSD1[1][2]. |
| Name | (1S,2R)-Tranylcypromine hydrochloride |
| CAS | 4548-34-9 |
| Formula | C9H12ClN |
| Molar Mass | 169.65 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. TetsuyaEzawa, et al. Amidation of carboxylic acids via the mixed carbonic carboxylic anhydrides and its application to synthesis of antidepressant (1S,2R)-tranylcypromine. Tetrahedron: Asymmetry. 15 December 2017;28(12):1690-1699. [2]. Valente S, et al. Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies. ACS Med Chem Lett. 2014 Dec 8;6(2):173-7. |