| Bioactivity | Neurokinin A (4-10) is a tachykinin NK2 receptor agonist. |
| Invitro | Neurokinin A (NKA) and its truncated form NKA(4-10) are potent spasmogens of human colon circular muscle, an action mediated exclusively via tachykinin NK2 receptors. A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) is performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK2 receptor in human colon circular muscle. A high density of NK2 receptors has been demonstrated in this tissue, using in vitro autoradiography and radioligand binding[1]. |
| Name | Neurokinin A(4-10) |
| CAS | 97559-35-8 |
| Sequence | Asp-Ser-Phe-Val-Gly-Leu-Met-NH2 |
| Shortening | DSFVGLM-NH2 |
| Formula | C34H54N8O10S |
| Molar Mass | 766.91 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |