Urotensin II, mouse_product_DataBase

Bioactivity	Urotensin II, mouse is an endogenous ligand for the orphan G-protein-coupled receptor GPR14 or SENR. Urotensin II, mouse is a potent vasoconstrictor. Urotensin II, mouse plays a physiological role in the central nervous system[1].
Invitro	This sequence of the C-terminus cyclic region of Urotensin II (U-II) is completely conserved in most species, including in the fish, frog, human, porcine, rat, and mouse, and it is thought to be essential for the agonistic activity of U-II. Urotensin II plays a physiological role in the central nervous system. Intracerebroventricular administration of Urotensin II induces anxiogenic-like behaviors in the elevated plus maze test and the hole-board test in mice in a dose-dependent manner, as do corticotropin releasing factor (CRF). The effective doses of Urotensin II are 10-100-fold higher than these of CRF in these tests[1].
Name	Urotensin II, mouse
Sequence	{pGlu}-His-Gly-Ala-Ala-Pro-Glu-Cys-Phe-Trp-Lys-Tyr-Cys-Ile (Disulfide bridge: Cys8-Cys13)
Shortening	{pGlu}-HGAAPECFWKYCI (Disulfide bridge: Cys8-Cys13)
Formula	C76H100N18O19S2
Molar Mass	1633.86
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

PeptideDB