Bioactivity | Necrocide 1 (compound (S)-38) a potent anticancer agent. Necrocide 1 has antiproliferative activity with an IC50 value of 0.48 and 2 nM for MCF-7 and PC3, respectively[1]. | ||||||||||||
Name | Necrocide 1 | ||||||||||||
CAS | 1247028-61-0 | ||||||||||||
Formula | C23H27NO3 | ||||||||||||
Molar Mass | 365.47 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Synthesis and Antitumor Effect in Vitro and in Vivo of Substituted 1,3-Dihydroindole-2-onesJ. Med. Chem., Article ASAPDOI: 10.1021/jm100763jPublication Date (Web): September 16, 2010 [2]. Christensen MK, et, al. Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones. J Med Chem. 2010 Oct 14;53(19):7140-5. |