Nav1.8-IN-9_product_DataBase

CAS: 2966089-14-3 F: C22H20F4N4O3S W: 496.48

Nav1.8-IN-9 (Example 16) is an orally active, potent Nav1.8 inhibitor with an IC50 of 0.084 nM. Nav1.8-IN-9 has the pote

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	Nav1.8-IN-9 (Example 16) is an orally active, potent Nav1.8 inhibitor with an IC50 of 0.084 nM. Nav1.8-IN-9 has the potential for widespread pain research[1].
In Vivo	Nav1.8-IN-9 (Example 16；30 mg/kg；单次口服) 在 1 小时、2 小时、4 小时均可抑制大鼠术后疼痛模型诱发的机械超敏反应[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.
CAS	2966089-14-3
Formula	C22H20F4N4O3S
Molar Mass	496.48
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Ting Liu, et al. Aromatic paracyclic Nav1.8 inhibitors and their applications. CN116462662A.

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