| Bioactivity | AX048 is an inhibitor for IVA cPLA2 with a XI(50) of 0.022 mole fraction and reveals an antihyperalgesic efficacy[1]. |
| In Vivo | AX048 (0-30 mg/kg，腹腔注射) 可以减少 Sprague-Dawley 大鼠的热痛觉过敏，ED50 为 1.2 mg/kg[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| CAS | 873079-69-7 |
| Formula | C22H41NO4 |
| Molar Mass | 383.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yaksh TL, et al., Systemic and intrathecal effects of a novel series of phospholipase A2 inhibitors on hyperalgesia and spinal prostaglandin E2 release. J Pharmacol Exp Ther. 2006 Jan;316(1):466-75. |