| Bioactivity | NVS MLLT-1 (compound 3) is a potent and selective MLLT1 inhibitor with Kd values of 0.18 µM, 0.24 µM, and 0.22 µM for wild-type, T1 mutants, and T3 mutants, respectively[1][2]. |
| Target | Kd: 0.18 µM (wild-type); Kd: 0.24 µM (T1 mutants); Kd: 0.22 µM (T3 mutants) |
| Name | NVS MLLT-1 |
| CAS | 2561471-13-2 |
| Formula | C23H23N5O |
| Molar Mass | 385.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ni X, et al. Structure and Inhibitor Binding Characterization of Oncogenic MLLT1 Mutants. ACS Chem Biol. 2021 Apr 16;16(4):571-578. [2]. Lee J, et al. The Promise and Peril of Chemical Probe Negative Controls. ACS Chem Biol. 2021 Apr 16;16(4):579-585. |