| Bioactivity | NT160 is a highly potent class-IIa HDAC inhibitor with an IC50 value of 0.046 μM. NT160 can be used for the research of central nervous system diseases[1]. |
| Invitro | NT160 对 IIa 类 HDAC4 亚型具有亲和力，IC50 值为 0.046 μM[1]。NT160 对 HDAC4、HDAC5、HDAC7 和 HDAC9 表现出非常高的抑制作用，IC50 值分别为 0.08 nM、1.2 nM、1.0 nM 和 0.9 nM[1]。 |
| Name | NT160 |
| CAS | 1418293-40-9 |
| Formula | C21H21F3N4O2 |
| Molar Mass | 418.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Turkman N, et al. Design, synthesis, biochemical evaluation, radiolabeling and in vivo imaging with high affinity class-IIa histone deacetylase inhibitor for molecular imaging and targeted therapy. Eur J Med Chem. 2022;228:114011. |