| Bioactivity | NSD3-IN-3 is a potent NSD3 inhibtor with an IC50 value of 1.86 μM. NSD3-IN-3 has anticancer activity and significantly inhibits the growth and proliferation of non-small cell lung cancer cell line H460[1]. |
| Invitro | NSD3-IN-3 (化合物 B2) (0-10 μM; 48 h) 在 10 μM 下完全抑制 H460 和 H1299 细胞中 H3K36me3 修饰[1]。NSD3-IN-3 (0-20 μM; 48 h) 抑制 H460 细胞的生长[1]。 Cell Viability Assay[1] Cell Line: |
| Name | NSD3-IN-3 |
| CAS | 445416-12-6 |
| Formula | C15H17N5O2S |
| Molar Mass | 331.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kong Ren, et al. Application of compound B2 as histone methyltransferase NSD3 inhibitor: China, CN109223795[P].2019-01-18. |