| Bioactivity | NSD3-IN-2 is a potent NSD3 inhibitor with an IC50 value of 17.97 μM. NSD3-IN-2 inhibits the growth and proliferation of non-small cell lung cancer cell lines H460, H1299 and H1650 with anti-cancer activity[1]. |
| Invitro | NSD3-IN-2 (化合物 C6) (30 μM; 48 h) 抑制 H460、H1299、H1560 细胞中 H3K36me3 的表达[1]。NSD3-IN-2 (50 μM; 7-16 d) 抑制 H460、H1299、H1560 细胞增殖，但对 A549 细胞无抑制作用[1]。 |
| Name | NSD3-IN-2 |
| CAS | 675190-57-5 |
| Formula | C17H15N5OS |
| Molar Mass | 337.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Piao Lianhua, et al. Application of compound C6 as histone methyltransferase NSD3 inhibitor: China, CN109223794[P].2019-01-18. |