| Bioactivity | NSC622608 is a V-domain Ig suppressor of T-cell activation (VISTA) ligand with an IC50 value of 4.8 μM[1]. |
| Target | IC50: 4.8 μM (VISTA) |
| Invitro | NSC622608 disrupts VISTA-VSIG-3 interaction with an IC50 value of 9.7 ± 0.3 μM[1]. |
| Name | NSC622608 |
| CAS | 2593254-90-9 |
| Formula | C9H12BrN3OS2 |
| Molar Mass | 322.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gabr MT, et al. Discovery and Optimization of Small-Molecule Ligands for V-Domain Ig Suppressor of T-Cell Activation (VISTA). J Am Chem Soc. 2020 Sep 23;142(38):16194-16198. |