| Bioactivity | NSC61610 disrupts hIL-18 binding to the ectromelia virus IL-18BP. NSC61610 inhibits hIL-18:ectvIL-18BP complex formation with an IC50 about 6 uM[1]. |
| Invitro | NSC61610 在 β 链 β5 和 β8 之间的 hIL-18 中的预测 Ki 值为 88 nM (虚拟筛选)[1]。NSC61610 抑制 hIL-18:ectvIL-18BP 复合物形成，IC50 约为 6 uM[1]。 |
| Name | NSC61610 |
| CAS | 500538-94-3 |
| Formula | C34H24N6O2 |
| Molar Mass | 548.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Krumm B, et al. Identification of small molecule inhibitors of Interleukin-18. Sci Rep. 2017 Mar 28;7(1):483. |