Bioactivity | NPS ALX Compound 4a dihydrochloride is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM[1]. |
Name | NPS ALX Compound 4a dihydrochloride |
CAS | 1781934-44-8 |
Formula | C25H27Cl2N3O2S |
Molar Mass | 504.47 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Isaac M, et al. 6-Bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindolesderivatives as novel, potent, and selective 5-HT6 receptor antagonists. Bioorg Med Chem Lett. 2000 Aug 7;10(15):1719-21. |