| Bioactivity | AChE/MAO-B-IN-3 (Compound D30) is a dual AChE and MAO-B inhibitor with IC50s of 0.0257 μM and 0.0456 μM against human AChE and MAO-B, respectively. AChE/MAO-B-IN-3 can be used for the research of Alzheimer’s disease[1]. |
| Invitro | AChE/MAO-B-IN-3 (Compound D30) 具有抗氧化活性，在 DPPH 自由基清除活性测试中的 IC50 为 0.246 ± 0.011 μM[1]。AChE/MAO-B-IN-3 抑制 β-淀粉样蛋白 1-42 (Aβ42)，IC50 为0.1780 ± 0.0074 μM[1]。 |
| Name | AChE/MAO-B-IN-3 |
| Formula | C24H28N2O4 |
| Molar Mass | 408.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sağlık BN, et al. Design, Synthesis, and In Vitro and In Silico Approaches of Novel Indanone Derivatives as Multifunctional Anti-Alzheimer Agents. ACS Omega. 2022 Dec 7;7(50):47378-47404. |