| Bioactivity | NPP1-IN-2 (compound 3h) is a potent and selective Ectonucleotide pyrophosphatase/phosphodiesterase-1 (NPP1) inhibitor with IC50 values of 0.55, 3.73 µM for NPP1, NPP3, respectively[1]. |
| Target | IC50: 0.55 µM (NPP1); 3.73 µM (NPP3) |
| Formula | C22H22N4OS |
| Molar Mass | 390.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tasleem M, et al. Synthesis, in vitro, and in silico studies of morpholine-based thiosemicarbazones as ectonucleotide pyrophosphatase/phosphodiesterase-1 and -3 inhibitors. Int J Biol Macromol. 2024 Mar 24;266(Pt 2):131068. |