| Bioactivity | NPC 17731 is a new bradykinin (BK) receptor antagonist. NPC 17731 antagonized both the contractile and relaxant responses caused by BK in longitudinal smooth muscle with IC50 of 23 and 29 nM, respectively[1]. |
| CAS | 147267-10-5 |
| Sequence | Arg-Arg-Pro-{Hyp}-Gly-Phe-Ser-{Hyp}-{Oic}-Arg |
| Shortening | RRP-{Hyp}-GFS-{Hyp}-{Oic}-R |
| Formula | C59H95N19O14 |
| Molar Mass | 1294.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Y S Medeiros, et al. Competitive and selective antagonistic action of NPC 17731 on bradykinin-induced relaxant and contractile responses of the guinea pig isolated ileum. Gen Pharmacol. 1995 Nov;26(7):1507-11. |
NPC 17731
CAS: 147267-10-5 F: C59H95N19O14 W: 1294.50
NPC 17731 is a new bradykinin (BK) receptor antagonist. NPC 17731 antagonized both the contractile and relaxant response
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