| Bioactivity | ML388 is a potent and selective hydroxyprostaglandin dehydrogenase (HPGD) inhibitor with an IC50 of 34 nM. ML388 induces PGE2 production in A549 cells and LNCaP prostate cancer cells[1]. |
| Target | IC50: 34 nM (hydroxyprostaglandin dehydrogenase (HPGD)) |
| CAS | 1537192-31-6 |
| Formula | C20H24N4 |
| Molar Mass | 320.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Damien Y. Duveau, et al. Discovery of two small molecule inhibitors, ML387 and ML388, of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase. |