Bioactivity | NN1177 is a long-acting GLP-1/glucagon receptor co-agonist. NN1177 can induce a dose-dependent body weight loss in diet-induced obese (DIO) mice. NN1177 can be used for the research of weight loss and metabolic control[1]. |
Name | NN1177 |
Sequence | H-Aib-QGT FTSDL SKYLE SKRAR EFVQW LL-K(-γGlu-γGlu-Ser-Glu-Ser-γGlu-γGlu-C18 diacid)-T-NH2 |
Formula | C225H3555N57O63 |
Molar Mass | 4866.56 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Simonsen L, et al. Preclinical evaluation of a protracted GLP-1/glucagon receptor co-agonist: Translational difficulties and pitfalls. PLoS One. 2022 Mar 4;17(3):e0264974. |