| Bioactivity | NH2-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. NH2-PEG9-acid also is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. |
| Invitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| Name | NH2-PEG9-acid |
| CAS | 756526-04-2 |
| Formula | C19H39NO10 |
| Molar Mass | 441.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
NH2-PEG9-acid
CAS: 756526-04-2 F: C19H39NO10 W: 441.51
NH2-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG
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