Bioactivity | NF(N-Me)GA(N-Me)IL is a biological active peptide. (This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis.) |
Name | NF(N-Me)GA(N-Me)IL |
CAS | 409085-42-3 |
Sequence | Asn-Phe-{Sar}-Ala-{Ile(N-Me)}-Leu |
Shortening | NF-{Sar}-A-{Ile(N-Me)}-L |
Formula | C32H51N7O8 |
Molar Mass | 661.79 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |