| Bioactivity | N36Mut(e,g) is a gp41-targeted HIV fusion peptide inhibitor. N36Mut(e,g) acts by disrupting the homotrimeric coiled-coil of N-terminal helices in the pre-hairpin intermediate to form heterotrimers[1]. |
| Sequence | Ser-Gly-Ile-Asp-Gln-Glu-Gln-Asn-Asn-Leu-Thr-Arg-Leu-Ile-Glu-Ala-Gln-Ile-His-Glu-Leu-Gln-Leu-Thr-Gln-Trp-Lys-Ile-Lys-Gln-Leu-Leu-Ala-Arg-Ile-Leu |
| Shortening | SGIDQEQNNLTRLIEAQIHELQLTQWKIKQLLARIL |
| Formula | C189H317N55O56 |
| Molar Mass | 4255.87 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bewley CA, et al. Design of a novel peptide inhibitor of HIV fusion that disrupts the internal trimeric coiled-coil of gp41. J Biol Chem. 2002 Apr 19;277(16):14238-45. |