Bioactivity | N-Desmethyl Zolmitriptan (183C91; DZT) is the active metabolite of the serotonin (5-HT) receptor subtype 5-HT1B and 5-HT1D agonist Zolmitriptan (HY-B0229). N-Desmethyl Zolmitriptan (183C91; DZT) is an agonist of 5-HT1B receptors and induces constriction in isolated human cerebral arteries (EC50=100 nM). |
CAS | 139264-35-0 |
Formula | C₁₅H₁₉N₃O₂ |
Molar Mass | 273.33 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Patel, et al. Systematic evaluation of matrix effect and cross-talk-free method for simultaneous determination of zolmitriptan and N-desmethyl zolmitriptan in human plasma: A sensitive LC-MS/MS method validation and its application to a clinical pharmacokinetic study. Biomed. Chromatogr. 30(3), 447-458 (2016). |