PeptideDB

N-Desmethyl Zolmitriptan

CAS: 139264-35-0 F: C₁₅H₁₉N₃O₂ W: 273.33

N-Desmethyl Zolmitriptan (183C91; DZT) is the active metabolite of the serotonin (5-HT) receptor subtype 5-HT1B and 5-HT
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Bioactivity N-Desmethyl Zolmitriptan (183C91; DZT) is the active metabolite of the serotonin (5-HT) receptor subtype 5-HT1B and 5-HT1D agonist Zolmitriptan (HY-B0229). N-Desmethyl Zolmitriptan (183C91; DZT) is an agonist of 5-HT1B receptors and induces constriction in isolated human cerebral arteries (EC50=100 nM).
CAS 139264-35-0
Formula C₁₅H₁₉N₃O₂
Molar Mass 273.33
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Patel, et al. Systematic evaluation of matrix effect and cross-talk-free method for simultaneous determination of zolmitriptan and N-desmethyl zolmitriptan in human plasma: A sensitive LC-MS/MS method validation and its application to a clinical pharmacokinetic study. Biomed. Chromatogr. 30(3), 447-458 (2016).