PeptideDB

N-Boc-PEG5-bromide

CAS: 1392499-32-9 F: C15H30BrNO6 W: 400.31

N-Boc-PEG5-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG5-bromide
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity N-Boc-PEG5-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Invitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Name N-Boc-PEG5-bromide
CAS 1392499-32-9
Formula C15H30BrNO6
Molar Mass 400.31
Transport Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month