| Bioactivity | Fmoc-Hyp(Bom)-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Hyp(Bom)-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]< | ||||||||||||
| Invitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. | ||||||||||||
| Name | Fmoc-Hyp(Bom)-OH | ||||||||||||
| CAS | 187223-15-0 | ||||||||||||
| Formula | C28H33N3O8 | ||||||||||||
| Molar Mass | 539.58 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Fmoc-Hyp(Bom)-OH
CAS: 187223-15-0 F: C28H33N3O8 W: 539.58
Fmoc-Hyp(Bom)-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Hyp(Bom)
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