| Bioactivity | N-Acetyl-5-hydroxytryptamine is a Melatonin precursor, and that it can potently activate TrkB receptor. | ||||||||||||
| Invitro | N-Acetyl-5-hydroxytryptamine (NAS), a precursor of Melatonin, is acetylated from serotonin by AANAT (arylalkylamine N-acetyltransferase). N-acetylserotonin activates TrkB receptor in a circadian rhythm. N-Acetyl-5-hydroxytryptamine swiftly activates TrkB in a circadian manner and exhibits antidepressant effect in a TrkB-dependent manner. N-Acetyl-5-hydroxytryptamine rapidly activates TrkB, but not TrkA or TrkC, in a neurotrophin- and MT3 receptor-independent manner[1]. | ||||||||||||
| Name | N-Acetyl-5-hydroxytryptamine | ||||||||||||
| CAS | 1210-83-9 | ||||||||||||
| Formula | C12H14N2O2 | ||||||||||||
| Molar Mass | 218.25 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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N-Acetyl-5-hydroxytryptamine
CAS: 1210-83-9 F: C12H14N2O2 W: 218.25
N-Acetyl-5-hydroxytryptamine is a Melatonin precursor, and that it can potently activate TrkB receptor.
Data collection：peptidedb@qq.com
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