| Bioactivity | DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. | |||||||||
| Invitro | DL-Homocysteine (0.1-0.5 mM) significantly enhances kynurenic acid (KYNA) production in rat cortical slices, and diministes the production of at 3.0, 5.0, and 10.0 mM, with the estimated IC50 of 6.4 (5.5-7.5) mM. DL-Homocysteine dose-dependently inhibits kynurenine aminotransferases I (KATI) activity at concentrations ≥0.2 mM, with an IC50 of 0.566 (0.442-0.724) mM, and the activity of KAT II with IC50 value of 8.046 (5.804-11.154) mM[1]. | |||||||||
| Name | DL-Homocysteine | |||||||||
| CAS | 454-29-5 | |||||||||
| Formula | C4H9NO2S | |||||||||
| Molar Mass | 135.19 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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