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N-Acetyl-2-carboxybenzenesulfonamide

CAS: 849067-18-1 F: C9H9NO5S W: 243.24

N-Acetyl-2-carboxybenzenesulfonamide is an orally active COX-1 and COX-2 inhibitor with IC50s of 0.06 μM and 0.25 μM,
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Bioactivity N-Acetyl-2-carboxybenzenesulfonamide is an orally active COX-1 and COX-2 inhibitor with IC50s of 0.06 μM and 0.25 μM, respectively. N-Acetyl-2-carboxybenzenesulfonamide shows anti-inflammatory activity[1].
Target IC50: 0.06 μM (COX-1), 0.25 μM (COX-2)
Name N-Acetyl-2-carboxybenzenesulfonamide
CAS 849067-18-1
Formula C9H9NO5S
Molar Mass 243.24
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. ChenQH, et al. Design, synthesis, and biological evaluation ofN-acetyl-2-carboxybenzenesulfonamides: a novel class of cyclooxygenase-2(COX-2) inhibitors. Bioorg Med Chem. 2005 Apr 1;13(7):2459-68. [2]. Chen QH, et al. Design, synthesis, and biological evaluation of N-acetyl-2-carboxybenzenesulfonamides: a novel class of cyclooxygenase-2 (COX-2) inhibitors. Bioorg Med Chem. 2005 Apr 1;13(7):2459-68.