Bioactivity | N-Acetyl-2-carboxybenzenesulfonamide is an orally active COX-1 and COX-2 inhibitor with IC50s of 0.06 μM and 0.25 μM, respectively. N-Acetyl-2-carboxybenzenesulfonamide shows anti-inflammatory activity[1]. |
Target | IC50: 0.06 μM (COX-1), 0.25 μM (COX-2) |
Name | N-Acetyl-2-carboxybenzenesulfonamide |
CAS | 849067-18-1 |
Formula | C9H9NO5S |
Molar Mass | 243.24 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. ChenQH, et al. Design, synthesis, and biological evaluation ofN-acetyl-2-carboxybenzenesulfonamides: a novel class of cyclooxygenase-2(COX-2) inhibitors. Bioorg Med Chem. 2005 Apr 1;13(7):2459-68. [2]. Chen QH, et al. Design, synthesis, and biological evaluation of N-acetyl-2-carboxybenzenesulfonamides: a novel class of cyclooxygenase-2 (COX-2) inhibitors. Bioorg Med Chem. 2005 Apr 1;13(7):2459-68. |