| Bioactivity | N-4′-(p-Trifluoromethylphenyl)butyl-DAB (compound 5g) is an agonit of lysosomal acid α-glucosidase (GAA). N-4′-(p-Trifluoromethylphenyl)butyl-DAB increases intracellular GAA activities dose-dependently, in Pompe patient's fibroblasts with the M519V mutation[1]. |
| Target | α-glucosidase (GAA) |
| Name | N-4′-(p-Trifluoromethylphenyl)butyl-DAB |
| Formula | C16H22F3NO3 |
| Molar Mass | 333.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kato A, et al. Design and Pharmacological Chaperone Effects of N-(4'-Phenylbutyl)-DAB Derivatives Targeting the Lipophilic Pocket of Lysosomal Acid α-Glucosidase. J Med Chem. 2023 Jul 13;66(13):9023-9039. |
N-4′-(p-Trifluoromethylphenyl)butyl-DAB
CAS: F: C16H22F3NO3 W: 333.35
N-4′-(p-Trifluoromethylphenyl)butyl-DAB (compound 5g) is an agonit of lysosomal acid α-glucosidase (GAA). N-4′-(p-Tri
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This product is for research use only, not for human use. We do not sell to patients.