Bioactivity | Myrtucommulone A is a non-prenylated acylphloroglucinol that can be isolated from Myrtus communis (myrtle). Myrtucommulone A interacts with the HSP60 chaperone and inhibits HSP60 chaperone activity. Myrtucommulone A decreases the expression of LRP130, LONP[1][2]. |
Invitro | Myrtucommulone A (0, 10, 30 µM) 在 37 ℃ 和 42 ℃ 时降低 LRP130 和 LONP 的表达[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Myrtucommulone A 相关抗体: |
CAS | 54247-21-1 |
Formula | C38H52O10 |
Molar Mass | 668.81 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wiechmann K, et al. Mitochondrial Chaperonin HSP60 Is the Apoptosis-Related Target for Myrtucommulone. Cell Chem Biol. 2017 May 18;24(5):614-623.e6. [2]. Hans M, et al. Stereoisomeric Composition of Natural Myrtucommulone A. J Nat Prod. 2015 Oct 23;78(10):2381-9. |