| Bioactivity | Myhc-α(334–352) is a sequence fragment of amino acid residues 334 to 352 of cardiac myosin heavy chain α. Myhc-α(334–352) is an immunodominant epitope that can induce autoimmune reactions in A/J mice, leading to the occurrence of myocarditis. Myhc-α(334–352) can be used to study the autoimmune pathways of myocarditis and dilated cardiomyopathy[1]. |
| CAS | 171675-09-5 |
| Sequence | Asp-Ser-Ala-Phe-Asp-Val-Leu-Ser-Phe-Thr-Ala-Glu-Glu-Lys-Ala-Gly-Val-Tyr-Lys |
| Shortening | DSAFDVLSFTAEEKAGVYK |
| Formula | C94H141N21O32 |
| Molar Mass | 2077.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Massilamany C, et al. Identification of novel mimicry epitopes for cardiac myosin heavy chain-α that induce autoimmune myocarditis in A/J mice[J]. Cellular immunology, 2011, 271(2): 438-449. |
Myhc-α(334–352)
CAS: 171675-09-5 F: C94H141N21O32 W: 2077.25
Myhc-α(334–352) is a sequence fragment of amino acid residues 334 to 352 of cardiac myosin heavy chain α. Myhc-α(334
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