| Bioactivity | Apolipoprotein KV domain (67-77) is an 11-amino acid peptide identified from the KV domain of human apolipoprotein a (ApoA) with antiangiogenic and antitumor activities. Apolipoprotein KV domain (67-77) targets the angiogenic c-Src/ERK pathway by blocking activation signals received from vascular endothelial growth factor (VEGF). Apolipoprotein KV domain (67-77) can be used in cancer research[1]. |
| CAS | 515170-17-9 |
| Sequence | Tyr-Thr-Met-Asn-Pro-Arg-Lys-Leu-Phe-Asp-Tyr |
| Shortening | YTMNPRKLFDY |
| Formula | C67H98N16O18S |
| Molar Mass | 1447.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yi Z F, et al. A novel peptide from human apolipoprotein (a) inhibits angiogenesis and tumor growth by targeting c‐Src phosphorylation in VEGF‐induced human umbilical endothelial cells[J]. International Journal of Cancer, 2009, 124(4): 843-852. |
Apolipoprotein KV domain (67-77)
CAS: 515170-17-9 F: C67H98N16O18S W: 1447.66
Apolipoprotein KV domain (67-77) is an 11-amino acid peptide identified from the KV domain of human apolipoprotein a (Ap
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