| Bioactivity | Myelin Basic Protein (MBP) (68-82), guinea pig is a fragment of myelin basic protein (MBP). | ||||||
| Invitro | Multiple sclerosis is the most common autoimmune disorder affecting the central nervous system. In this study, whole blood samples are analyzed for activation capacity and the activatability of CD4+ and CD8+ T-lymphocytes by human total myelin basic protein (MBP), human MBP 104-118 fragment, and guinea pig MBP (68-82) fragment. A significant increase in the number of activated T-lymphocytes was observed in the whole blood. For all three tested MBPs, this increase in activated CD4+ and CD8+ T-lymphocytes is statistically significant (phuMBP-104-118>guinea pig MBP (68-82))[1]. | ||||||
| Name | Myelin Basic Protein (MBP) (68-82), guinea pig | ||||||
| CAS | 98474-59-0 | ||||||
| Sequence | Tyr-Gly-Ser-Leu-Pro-Gln-Lys-Ser-Gln-Arg-Ser-Gln-Asp-Glu-Asn | ||||||
| Shortening | YGSLPQKSQRSQDEN | ||||||
| Formula | C71H113N23O28 | ||||||
| Molar Mass | 1736.79 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |