| Bioactivity | Mycobactin-IN-2 (compound 49) is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-2 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway[1]. |
| Target | Mycobactin |
| Invitro | Mycobactin-IN-2 exhibits notable activity against M. tuberculosis in iron-impoverished media with MIC90 8 μg/mL[1]. |
| Name | Mycobactin-IN-2 |
| CAS | 421573-09-3 |
| Formula | C15H13BrN2O |
| Molar Mass | 317.18 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shyam M, et, al. Mycobactin Analogues with Excellent Pharmacokinetic Profile Demonstrate Potent Antitubercular Specific Activity and Exceptional Efflux Pump Inhibition. J Med Chem. 2022 Jan 13;65(1):234-256. |
Mycobactin-IN-2
CAS: 421573-09-3 F: C15H13BrN2O W: 317.18
Mycobactin-IN-2 (compound 49) is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-2 binds to sali
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