Bioactivity | Mtb-cyt-bd oxidase-IN-3 (compound 1u) is a Mycobacterium tuberculosis cytochrome bd oxidase (Mtb cyt-bd oxidase) inhibitor with an IC50 value of 0.36 μM. Mtb-cyt-bd oxidase-IN-3 inhibits the growth of Mycobacterium tuberculosis (MIC=32 μM). Mtb-cyt-bd oxidase-IN-3 can be used in tuberculosis research[1]. |
Invitro | Mtb-cyt-bd oxidase-IN-3 inhibits the growth of Mycobacterium tuberculosis and Mycobacterium smegmatis with MICs of 32 μM and >512 μM, respectively[1]. |
Name | Mtb-cyt-bd oxidase-IN-3 |
Formula | C26H35NO2 |
Molar Mass | 393.56 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Lawer A, et al. Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of Mycobacterium tuberculosis Cytochrome bd Oxidase. ACS Med Chem Lett. 2022 Sep 26;13(10):1663-1669. |