| Bioactivity | Monoamine oxidase is an enzyme composed of different polypeptides. Monoamine oxidation catalyzes the oxidative deamination of various biological amines in brain and peripheral tissues by producing hydrogen peroxide. Monoamine oxidase plays an important role in maintaining the regulation of synaptic transmission, emotional behavior and other brain functions[1][2]. |
| Invitro | Monoamine oxidase 有一些同工酶，其中最典型的是单胺氧化酶 (MAO) A 和 MAOB 。MAOA 通常被低浓度氯吉林 (Clorgyline，HY-14197A) 抑制，MAOB 通常被低浓度的 l-盐酸司立吉林抑制[3]。 |
| Name | Monoamine oxidase |
| CAS | 9001-66-5 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shih JC, et al. Monoamine oxidase: from genes to behavior. Annu Rev Neurosci. 1999;22:197-217. [2]. Bortolato M, et al. Monoamine oxidase inactivation: from pathophysiology to therapeutics. Adv Drug Deliv Rev. 2008 Oct-Nov;60(13-14):1527-33. [3]. Youdim MB, et al. The therapeutic potential of monoamine oxidase inhibitors. Nat Rev Neurosci. 2006 Apr;7(4):295-309. |