| Bioactivity | GluN2B receptor modulator-1 is a selective GluN2B negative allosteric modulator with an IC50 value of 31 nM. |
| Name | GluN2B receptor modulator-1 |
| CAS | 2222010-71-9 |
| Formula | C17H15F3N4O2S |
| Molar Mass | 396.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chrovian CC, et al. Design, Synthesis, and Preclinical Evaluation of 3-Methyl-6-(5-thiophenyl)-1,3-dihydro-imidazo[4,5-b]pyridin-2-ones as Selective GluN2B Negative Allosteric Modulators for the Treatment of Mood Disorders. J Med Chem. 2020 Sep 10;63(17): |