| Bioactivity | Milacemide (hydrochloride), a glycinamide derivative, is an orally active MAO-B inhibitor with anticonvulsant activity. Milacemide (hydrochloride) reduces the levels of dihydroxyphenylacetic acid and homovanilic acid, but increases the levels of dopamine and serotonin in the caudate nucleus. Milacemide (hydrochloride) is promising for research of Alzheimer's disease[1]. |
| CAS | 76990-85-7 |
| Formula | C7H17ClN2O |
| Molar Mass | 180.68 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Janssens de Varebeke P, et al. Milacemide, the selective substrate and enzyme-activated specific inhibitor of monoamine oxidase B, increases dopamine but not serotonin in caudate nucleus of rhesus monkey. Neurochem Int. 1990;17(2):325-9. [2]. Colombo M, et al. MAO activity, metabolism and anticonvulsant activity of milacemide in rats and mice. J Neural Transm Suppl. 1990;32:123-9. |
Milacemide hydrochloride
CAS: 76990-85-7 F: C7H17ClN2O W: 180.68
Milacemide (hydrochloride), a glycinamide derivative, is an orally active MAO-B inhibitor with anticonvulsant activity.
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This product is for research use only, not for human use. We do not sell to patients.