| Bioactivity | L-748328 is a potent and selective human β3-adrenergic receptor antagonist. L-748328 has a Ki of 3.7 nM against human cloned β3-AR expressed in Chinese hamster ovary (CHO) cells. In addition, L-748328 inhibits the lipolytic response induced by the β3-AR agonist L-742791 in isolated non-human primate adipocytes[1]. |
| CAS | 244192-93-6 |
| Formula | C23H27N3O6S2 |
| Molar Mass | 505.61 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Candelore M R, et al. Potent and selective human β3-adrenergic receptor antagonists[J]. Journal of Pharmacology and Experimental Therapeutics, 1999, 290(2): 649-655. |
L-748328
CAS: 244192-93-6 F: C23H27N3O6S2 W: 505.61
L-748328 is a potent and selective human β3-adrenergic receptor antagonist. L-748328 has a Ki of 3.7 nM against human c
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