| Bioactivity | Microcin J25 (MccJ25) is a cyclic peptide antibiotic consisting of 21 unmodified amino acid residues. Microcin J25 inhibits DNA-dependent RNA polymerase (RNAP) of Gram-negative bacteria. Microcin J25 has antibacterial activity[1][2]. |
| CAS | 622787-00-2 |
| Sequence | cyclo(Gly-Gly-Ala-Gly-His-Val-Pro-Glu-Tyr-Phe-Val-Gly-Ile-Gly-Thr-Pro-Ile-Ser-Phe-Tyr-Gly) |
| Shortening | cyclo(GGAGHVPEYFVGIGTPISFYG) |
| Formula | C101H139N23O27 |
| Molar Mass | 2107.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wilson KA, et al. Structure of microcin J25, a peptide inhibitor of bacterial RNA polymerase, is a lassoed tail. J Am Chem Soc. 2003 Oct 15;125(41):12475-83. [2]. Delgado MA, et al. Escherichia coli RNA polymerase is the target of the cyclopeptide antibiotic microcin J25. J Bacteriol. 2001 Aug;183(15):4543-50. |
Microcin J25
CAS: 622787-00-2 F: C101H139N23O27 W: 2107.32
Microcin J25 (MccJ25) is a cyclic peptide antibiotic consisting of 21 unmodified amino acid residues. Microcin J25 inhib
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