Mezilamine

CAS: 50335-55-2 F: C11H18ClN5S W: 287.81

Mezilamine is a potent antidopaminergic agent. Mezilamine induces a concentration dependent increase in the electrically

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Bioactivity	Mezilamine is a potent antidopaminergic agent. Mezilamine induces a concentration dependent increase in the electrically stimulated overflow of 3H-noradrenaline from rat cortical slices, without affecting the basal overflow. Mezilamine acts as a presynaptic α-adrenoceptor antagonist and a postsynaptic α-adrenoceptor agonist[1].
Invitro	Mezilamine (1, 5, 10 μM) 导致 3H 刺激的溢出浓度依赖性增加，而不影响皮质切片的自发流出[1]。
Name	Mezilamine
CAS	50335-55-2
Formula	C11H18ClN5S
Molar Mass	287.81
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. G Le Fur, et al. Mezilamine, a new dopamine antagonist, blocks presynaptic but stimulates postsynaptic alpha-adrenoceptors. Eur J Pharmacol. 1979 Oct 15;58(4):359-67.

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