| Bioactivity | Mesyl Salvinorin B is a potent and selective kappa opioid receptor (KOP-r) agonist. Mesyl Salvinorin B prevents the ADE (Alcohol deprivation effect) in mice. Mesyl Salvinorin B dose-dependently reduces alcohol intake and preference in CED (chronic escalation drinking) mice[1][2]. |
| In Vivo | Mesyl Salvinorin B (0.3, 1, 3 mg/kg; i.p.; once) 3 mg/kg 时可在雄性和雌性小鼠中预防ADE[1]。 Animal Model: |
| Name | Mesyl Salvinorin B |
| CAS | 862073-79-8 |
| Formula | C22H28O9S |
| Molar Mass | 468.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhou Y, et al. Effects of mesyl salvinorin B alone and in combination with naltrexone on alcohol deprivation effect in male and female mice. Neurosci Lett. 2018 Apr 23;673:19-23. [2]. Zhou Y, et al. Synergistic blockade of alcohol escalation drinking in mice by a combination of novel kappa opioid receptor agonist Mesyl Salvinorin B and naltrexone. Brain Res. 2017 May 1;1662:75-86. |
Mesyl Salvinorin B
CAS: 862073-79-8 F: C22H28O9S W: 468.52
Mesyl Salvinorin B is a potent and selective kappa opioid receptor (KOP-r) agonist. Mesyl Salvinorin B prevents the ADE
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.