| Bioactivity | Mer-NF5003F is a sesquiterpene originally isolated from Stachybotrys with diverse biological activities. It inhibits avian myeloblastosis virus (AMV) protease (IC50=7.8 μM).1 Mer-NF5003F inhibits sialyltransferase 6N (ST6N), ST3O, and ST3N (IC50s=0.61, 6.7, and 10 μg/mL, respectively), as well as fucosyltransferase (IC50=11.3 μg/mL). It is active against herpes simplex virus 1 (HSV-1) in vitro (IC50=4.32 μg/mL).3 Mer-NF5003F is also active against the multidrug-resistant P. falciparum strain K1 (IC50=0.85 μg/mL). |
| CAS | 149598-70-9 |
| Formula | C23H30O5 |
| Molar Mass | 386.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kaneto, et al. Mer-NF5003B, E and F, novel sesquiterpenoids as avian myeloblastosis virus protease inhibitors produced by Stachybotrys sp. J. Antibiot. (Tokyo) 47(6), 727-730 (1994). |
Mer-NF5003F
CAS: 149598-70-9 F: C23H30O5 W: 386.48
Mer-NF5003F is a sesquiterpene originally isolated from Stachybotrys with diverse biological activities. It inhibits avi
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